Be careful to connect the USB cable in the correct orientation, because it can be connected backwards! The pin #1 has an arrow on the connector body, and has a red wire to it. So at the very least on the Aquaero you will need the Molex power connected, and a five pin USB cable connected to the motherboard or USB splitter like a Hubby7.
The Aquasuite software will not install if it does not detect any Aquaero devices first. The RPM header sends a fake RPM signal to the motherboard CPU fan header. The only connections I use are the Power, USB 5 pin, I have four temp sensors plugged in, all four fan channels, the Aquabus high, and the RPM. Here is a look at the back just after installing these, the Aquaero XT is on the bottom, with the Aquaero LT slave unit on top. The beautiful thing about Aquasuite is that once you have it all setup, you can have it set to start with Windows, it runs in the background monitoring, and controlling everything you have it set up to do automatically. I’ve been using Aquasuite for over six years now, but I still do not use all the aspects of the software, so I will not be to covering those areas that I don’t use myself. The Aquasuite software can be used in a fairly simple setup, all the way to very complex builds. So my goal here is to use many screen shots, and walk you through how I set up my two Aquaeros and the Aquasuite software on this particular build. It is not always easy to visualize what to do by merely reading instructions. None of the links on the OP work anymore, and if I posted it there it would just get lost. There is an OCN Aquaero Owners Club if you haven't already seen it. So I'm posting it in it's own thread, and on my build log. I was originally making this guide for my build log The Big Red "Devastator", but I thought more people would be able to find it if I made a separate thread.
It was getting rather dated at this point, and was based on the Aquaero 5. He passed away several years ago, and all of the links to his guide are broken or missing.
I actually got started with my Aquaero by reading a guide written by Namron, a member here on OCN. Here’s a link to the most recent version from Aqua Compter, as of this writing it was last updated in November of 2016! The official documentation is not updated very often. The accompanying Aquasuite software is truly incredible and very powerful software! However, it can be a little intimidating if you have never used it before, and there is definitely a learning curve involved. The Aquaero fan controllers are in my opinion the very best at controlling and monitoring your fans, pumps, and other accessories related to water or even air cooled PCs.